By Irfana Parveen

B.Sc (Psychiatry Ward)

28 November 2021
Medically reviewed by
Sumayya Salam
Pharm D
Dangers of Mixing Prozac And Alcohol
Table of Contents

Prozac, recognized by its generic name fluoxetine, is a prescription medication used to treat the major depressive disorder (MDD), bulimia nervosa (an eating disorder), obsessive-compulsive disorder, bipolar disorder, panic disorder, and premenstrual dysphoric disorder (PMDD).

Prozac works by affecting certain chemical messengers responsible for the communication between brain cells and helps people suffering from depression, panic attacks, anxiety, or obsessive-compulsive disorder (K.W. and Bymaster, F.P., 2005).

Fluoxetine comes under a drug class called selective serotonin reuptake inhibitors (SSRI). You can order Fluoxetine online from a certified online pharmacy, it is recommended to get a doctor's prescription first.

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Is It Safe To Consume Alcohol With Prozac?

Consuming alcohol can increase the adverse effects of Prozac. One should avoid taking alcohol along with any anti-depressant medication. On the other hand, taking alcohol also results in a decrease in the effectiveness of Prozac.

Long-term consumption of Prozac along with alcohol can cause liver /kidney issues, heart damage, and blood sugar problems.(Raufdeen, F. and Singh, N., 2016)

Effects Of Drinking Prozac Along With Alcohol?

Taking Prozac along with alcohol will result in the following side effects:

Study On Alcohol As An Anti-Depressant:

A study published in the journal ‘Nature Communications.’ found that Alcohol activates the same brain pathway as for drugs with fast-acting anti-depressant effects.

According to this study, the study found out that Alcohol followed the same biochemical pathway as rapid anti-depressants in the animals, with behavioral effects comparable to those seen in people. Single doses of rapid anti-depressants like Ketamine have been shown in recent years to relieve depressive symptoms around two hours and last for up to two weeks, even in people who are resistant to traditional anti-depressants.

Raab and her colleagues found that a single dose of intoxicating alcohol blocked NMDA receptors (proteins associated with learning and memory) while working in conjunction with autism-related protein FMRP and transformed the GABA acid from an inhibitor into a stimulator of neural activity. The researchers found that these biochemical changes resulted in non-depressive behaviors for 24 hours.

The researchers, led by Kimberly Raab-Graham, Ph.D. of Wake Forest School of Medicine at Wake Forest Baptist Medical Center in Winston-Salem, NC, warn that their findings in no way represent that people suffering from depression should resort to alcohol as a cure. (Pettinati, H.M., 2004)

Key Takeaways:

  • Prozac is an anti-depressant used to treat major depressive disorder.
  • It is not safe to consume Prozac and alcohol together.
  • Study has found out that alcohol works similarly to anti-depressants.
  • It is not advised to use alcohol as an anti-depressant.
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