By Irfana
B.Sc (Psychiatry Ward)
06 December 2021 -
Medically reviewed by
D. Pharm
Venlafaxine And Alcohol
Table of Contents

Venlafaxine is an antidepressant drug prescribed to treat depression, anxiety, and panic attacks. It works by increasing the levels of neurotransmitters in the brain that cause sensations of pleasure and reward. This medicine can help alleviate symptoms of depression and anxiety by boosting neurotransmitters like serotonin. However, the particular mechanism of action of Venlafaxine remains unknown. 

Venlafaxine is not available over the counter you always need prescription for these medicine. Buy Venlafaxine online from a verified online pharmacy.

Forms and Strength

Immediate release oral tablets - 25 mg, 37.5 mg, 50 mg, 75 mg, 100 mg

Extended release oral tablets - 37.5 mg, 75 mg, 150 mg, 225 mg


The recommended starting dose of Venlafaxine is 75 milligrams per day. This could be increased to a maximum amount of 375mg over time. If you have liver or renal problems, your doctor may prescribe a lesser dose.

Venlafaxine pills and capsules are available in both immediate and extended-release formulations. The way you take them is determined by the type you've been given.

For depression

Immediate Release - 

75 mg/day orally divided every 8-12 hours at first; may be increased by 75 mg/day no more than once every four days.

Moderate: 225 mg/day, split every 8-12 hours orally

Severe: 375 mg/day, split every 8-12 hours orally

Extended-Release - 

Initially, take 37.5-75 mg orally once daily; after four days, increase by 75 mg/day; do not exceed 225 mg/day.

Drug Interactions

When you combine Venlafaxine with other sleepy medicines, side effects can be amplified. Before taking an opioid prescription, a sleeping pill, a muscle relaxant, or a treatment for anxiety or seizures, consult your doctor.

(Holliday, S.M. and Benfield, P., 1995)

Venlafaxine Interaction With Alcohol

Alcohol is occasionally used to alleviate depression symptoms, but it can also increase long-term mood problems such as depression or anxiety. It's not always clear whether depression causes alcohol abuse or the other way around.

Nonetheless, it is vital to understand that drinking alcohol frequently exacerbates mental health issues in the long run. Although there hasn't been much well-controlled research on the effects of mixing alcohol and Venlafaxine, specific side effects of either substance may be exacerbated by combining them. 

Alcoholism has also been linked to a slew of other health problems, including liver disease, pancreatitis, and various cancers. When a small amount of alcohol may not be harmful when using Venlafaxine, it is not suggested to drink alcohol while taking an antidepressant.(Ciraulo, D.A., Barlow, D.H., Gulliver, S.B., Farchione, T., Morissette, S.B., Kamholz, B.W., Eisenmenger, K., Brown, B., Devine, E., Brown, T.A. and Knapp, C.M., 2013)

What's on your mind?

Start a conversation, Post with kindness.