Treat Bouts Of Anxiety-Induced Insomnia With Zopiclone

Zopiclone is a well-known medication that works to help one in getting rid of their insomnia. It does not work by itself but is a great help when used in combination with strategies that aim to fix one’s sleep schedule. Furthermore, the reason this drug is mentioned on our website is because there is a correlation between anxiety and insomnia. It has been found that anxiety could be a big reason one suffers from insomnia. This leads to an unbalanced sleep schedule and causes a snowball effect in worsening the insomnia. Here, zopiclone is of great help as it allows one to get some quality rest no matter what is going on in their mind.

A Brief Overview Of Zopiclone And Its Relation With The Benzodiazepine Drugs

Zopiclone is a non- benzodiazepine drug that belongs to the class of psychoactive drugs having many similarities to benzodiazepines in nature. They are commonly used in the treatment of sleep problems.

The pharmacodynamics of non-benzodiazepines are almost the same as benzodiazepine drugs. Hence exhibiting similar effects, benefits, and risks. However, the two have completely different chemical structures. Therefore, they are entirely unrelated to benzodiazepines on a molecular level.

The efficiency potential is of non -benzodiazepines is more than that of benzodiazepine, making it a suitable substitute for them.

Its sedative composition decreases the sleep initiation time, reduces the early awakening, and increases overall sleep hours.

Mechanism Of Zopiclone

Zopiclone Mechanism of Action

The significant action is mechanized on the central nervous system. It is an agonist, which means a chemical that ties to the receptor. GABA is the crucial receptor responsible for regulating calmness by reducing excess brain activity.

It blocks the message transmission from the nerve to the brain that helps a person feel relaxed and at peace. Zopiclone enhances the biological effects of GABA, which helps an insomniac person to fall asleep quickly by eliminating wakefulness during the night-time.

Zopiclone For Anxiety-Induced Insomnia

As mentioned above, insomnia is a common sign that many individuals with anxiety face. Since the early ’80s, neurologists have recommended Zopiclone to treat acute insomnia caused due to anxiety.

Doctors commonly prescribe this medication for hypnotic therapy to help anxiety-induced insomniac patients sleep quickly and prevent them from waking up too early or repeatedly during the night. Which then results in reduced anxiety, increased energy and cognition during the day.

While fulfilling the hypnotic task, it does not source the change in memory function. A person does not feel lost or impaired with the past memory for the following day. As stated by Hajak, Göran in 1999. “A comparative assessment of the risks and benefits of Zopiclone.” Drug safety.

Side Effects

Zopiclone Side Effects

Zopiclone is the first of the Cyclopyrrolone, a new class of psychotherapeutic drugs possessing of high efficacy and low toxicity.

Physiological side effects: include: dizziness or drowsiness due to its depressive effects on the CNS, impairing judgment, focus, or mobility. Hence causing accidents, falls, or severe injuries.

Physical side effects: such as a dry mouth or bitter/metallic taste in the mouth, headache, abdominal pain (typically lasts for the first few days), itching, skin rash

Psychological side effects: Amnesia, hallucinations, delusions, depressions, bipolar disorder, epilepsy, irritability

Warnings And Precautions

Zopiclone Warnings and Precautions
  1. Do not consume this medication during pregnancy as it can cause the baby to be premature or underweight. It can also cause severe post-partum withdrawal symptoms. Consumption of Zopiclone while breastfeeding is not recommended either.
  2. Zopiclone should not be used by people having respiratory failure, severe sleep apnea syndrome, severe liver problems, or those who retain hypersensitivity to the drug.
  3. Patients below the age of 18 or over the age of 65 are advised to avoid using this drug as they tend to be more sensitive to its effects.
  4. Refrain from performing any kind of hazardous activities, operating heavy machinery, or driving while under the influence of Zopiclone.

Withdrawal Syndrome Of Zopiclone

In contrast with other drugs, Zopiclone has a relatively lower dependence tolerance for those who use it for medicinal purposes. However, doctors do not recommend it for long-term use to prevent withdrawal symptoms.

Discontinuation of Zopiclone after prolonged use (more than four weeks) or more than recommended may cause serious adverse effects after abrupt withdrawal, including:

  • Headache
  • sleeplessness
  • feelings of agitation or confusion or panic or irritability
  • muscle pain or cramps or aches 
  • rapid heartbeat or arrhythmia
  • shaking
  • sweating
  • discomfort in the stomach or gut

Zopiclone Interactions

Inform your healthcare provider before using any other substance along with Zopiclone, as the interaction can lead to extremely risky and dangerous side effects.

When combined with any other substance (drug or alcohol), Zopiclone can create an additive effect, significantly increasing the potential of an overdose by considerably amplifying the risks of adverse effects.

Due to the increased possibility for dependence, tolerance, and addiction, alcohol or any other substances should be avoided at all costs while under the influence of Zopiclone.

Recreational Use And Abuse Of Zopiclone

If Zopiclone is consumed frequently for an extended period of time, a person will build up a high tolerance for it, motivating the urge to consume it more frequently at higher doses. Drug abuse can occur either of the two ways:

  • When the use of the drug is continued against medical advice for long-term
  • Wherein the drug is consumed to obtain a recreational high

Retaining non-medicinal uses, the drug has a high potential for dependence, addiction, and extreme dosage escalation. It is commonly combined with alcohol to create a hypnotic, sedative, euphoria-like state.

Research has concluded that Zopiclone may be more addictive than benzodiazepines. Individuals having a history of substance abuse have resulted in being at an increased risk of Zopiclone abuse. This has been well explained by Cimolai, Nevio. in 2007 “Zopiclone: is it a pharmacologic agent for abuse?” Canadian family physician.

Lastly,

Before consuming any medication, it is crucial to understand your medical history and reactions; therefore, it is important for you to consult a healthcare professional before considering Zopiclone.

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