Published on 14 September 2022

Is It Possible To Take Ambien And Weed Together?

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Marijuana is a psychoactive substance that results in intoxication effects on the body; using it for a prolonged period will increase the effect of drugs and developmental disorders like acute psychosis. Studies show that Marijuana will result in a high risk of lung cancer for people who smoke and an increased heart rate.

Combining ambien and marijuana will show symptoms like drowsiness, lethargy, motor activity, nausea, and vomiting.

Let us see how the ambien and weed are working in your system.

What Is Ambien?

Ambien is an imidazopyridine with rapid hypnotic action. Ambien shortens the delay of sleep onset, reduces the number of waking episodes, increases the total duration of sleep, and improves quality.

How Does Ambien Work?

Ambien is a central nervous system depressant. It can slow down brain activity. Most central nervous system depressants affect the brain; on the other hand, they enhance the activity of gamma-aminobutyric acid (GABA), a natural chemical in the brain which passes messages between cells. GABA works by slowing down brain activity.

It binds to specific receptors of the GABA-responsible for the modulation of the chloride channels and thereby induces sleep.

Ambien belongs to a group of Non- benzodiazepines, a sedative drug effect; it wins immediate-release relaxation and produces a cal effect which makes you feel drowsy and fall asleep quickly.

Indications And Dose Of Ambien


Occasional insomnia, transient insomnia, chronic insomnia

  • The dosage should be adapted individually. In all cases, take the drug before going to bed.
  • The treatment duration should be as short as possible, from a few days to a maximum of 4 weeks.


It is available as immediate-release, extended-release (CR), sublingual tablets, and oral sprays.

Vaporizers dose- 6.25 mg for women and either 6.25 or 12.5 mg for males.


  • Initial dose- 6.25 mg for women and either 6.25 or 12.5 mg for males.
  • It can be increased to 12.5 mg if 6.25 mg is ineffective.

What Is Weed?

The dried, greenish-grey blooms of the Cannabis sativa plant are what makeup marijuana. It is also called Mary Jane, marijuana, herb, pot, grass, bud, and many more slang terms.

People smoke weed in pipes, water pipes, or blunts wrapped in cigar paper. Brewing tea is often possible from weed when marketed or used medicinally.

Edible foods like brownies, biscuits, and sweets also use weeds. Using vaporizers to consume marijuana is becoming more popular.

The primary psychoactive component of weed, delta-9-tetrahydrocannabinol, produces intoxicating effects (THC) of weed. The substance is present in resin produced by the leaves and buds of the female plant.

The plant has more than 500 chemicals (including more than 100 cannabinoids) chemically related to THC. The second most popular psychoactive substance in the US is marijuana, after alcohol. Over 11.8 million young adults used marijuana in the year before 2018.

Frequently Asked Questions

While consuming Ambien and weed products will cause drowsiness and dizziness, increasing the risk of side effects. If you are using cannabis, inform your doctor before taking the drug.
While taking ambien, do not mix it with opioids, benzodiazepines, and alcohol group of drugs, because it will lead to extreme levels of tiredness, and falling sometimes leads to dangerous activity.
At the start, you will find it difficult to cope with symptoms simply due to the active ingredient inside the fat cells in your body. There are out of some coping therapies available to enhance and relieve the side effects.
You should not mix Adderall with Ambien as it is dangerous and may lead to heart failure.

Statistics And Facts About Weed Use In The USA

In 2019, 48.2 million Americans, or about 18% of the population, consumed weed, making it the most widely used narcotic that is federally banned in the country.

According to a recent study, 3 in 10 marijuana users have a marijuana use disorder. The risk is higher for those who start using the drug before 18 years, according to the study.

Teenagers still have developing brains, and young children are most vulnerable to the side effects of weed.

Frequent use increases the risk of psychosis and schizophrenia in some users. Consuming weed during pregnancy increases the risk of complications in pregnancy.

What Are The Effects Of Weed?

When marijuana (weed) is smoked, the THC and other plant compounds travel from the lungs to the bloodstream and the brain. It produces a pleasant euphoria and a sense of relaxation.

Other Common Effects Include:

  • Altered senses
  • Heightened sensory perception (e.g., brighter colors), laughter
  • Altered perception of time
  • Changes in mood
  • Anxiety, fear, distrust, or panic
  • Impaired body movement
  • Difficulty with thinking and problem-solving
  • Impaired memory and learning
  • Hallucinations and paranoia
  • Breathing problems
  • Possible harm to the brain of the fetus in pregnant women
  • Weed consumed in foods or beverages causes delayed effects, usually appearing after 30 minutes to 1 hour because the drug must first pass through the digestive system.
  • Smoking weed produces a faster, shorter-lived high than taking it orally.
  • Those who have ingested significant dosages may develop an acute psychosis, which includes hallucinations, delusions, and a loss of sense of self.
  • These unpleasant but brief side effects are distinct from more persistent psychotic disorders, including schizophrenia, due to marijuana usage in susceptible people.

Mixing Weed And Ambien

People who take Ambien and Weed will experience the effects of both substances. Consuming significantly more weed and Ambien results in sedation and lethargy, as well as the synergistic effects that result from mixing the two drugs.

Combined use of weed and Ambien may result in:

  • reduced motor reflexes
  • dizziness
  • nausea and vomiting

Other effects include euphoria, depression, irritability, or all three. Concomitant use of weed and Ambien dramatically increase drowsiness, which can easily lead to coma, respiratory depression, seizures, and death.

How Do Weed And Ambien Act Together?

The concentration of the inhibitory neurotransmitter GABA, which is present in the spinal cord and brain stem, and its impact on neuronal transmitters affect the primary effect of weed.

Mixing weed and Ambien produce unpredictable side effects. It lowers dopamine levels in the brain.A little to moderate dose of marijuana taken with Ambien can cause sleep disorders like sleep apnea.

The US Centers for Disease Control and Prevention (CDC) recently released statistics showing that other drugs like Ambien were responsible for increased ER visits and hospitalizations brought on by excessive marijuana usage.

Marijuana inhibits the metabolism of Ambien. A person may experience a delay in the relief of their underlying symptoms if their Ambien dosage is off.

Potential Side Effects Of Mixing Ambien And Weed

Many people consume weed for its mood-altering and relaxing effects. High doses of marijuana can lead to anxiety and depression. If you take weed with Ambien, you are likely to have side effects.
Doctors may refuse to write an Ambien prescription for those who are on weed.

One of the milder side effects of combining weed and Ambien seen in teens is scrolling. Scrolling occurs as a result of smoking marijuana. It is recurring vomiting. The individual is violently sick, vomits, and screams due to pain.

Potential side effects of mixing Ambien and Weed may include:

  • Loss of motor skills
  • Poor or lack of coordination
  • Lowered blood pressure
  • Short-term memory loss
  • Increased heart rate
  • Increased blood pressure
  • Anxiety
  • Paranoia
  • Increased energy
  • Increased motivation

People who combine Ambien with cannabis may experience hallucinations. Weed produces different effects in different people, making it a potent drug.

Ambien And Weed With Antidepressants

People who use marijuana get euphoric and can unwind. Heavy marijuana usage, however, may have unfavorable effects. It may increase Anxiety and depression in users. Over time, depression can worsen in a person.

Some use antidepressant drugs for depression and Anxiety caused by weed use. People who take antidepressants also use Ambien and weed.

They may be unaware of the side effects and repercussions of using Ambien, weed, and certain antidepressants. There are hardly any studies on marijuana, Ambien, and antidepressants.

Treatments For Weed (Marijuana) Use Disorders

Cognitive-behavioral therapy:

The goal is to improve self-control, eliminate drug use, and treat issues that frequently co-occur. CBT entails ways to recognize and rectify problematic behaviors.

Contingency management:

A therapeutic method of management - observes target behavior and the provision (or withdrawal) of concrete, constructive rewards when the target behavior occurs (or does not).

Motivational enhancement therapy:

An approach to intervention for rapid internally motivated change; the therapy does not aim to treat the patient but rather to activate their internal resources for change and participation in the process.

There are no medications approved for the treatment of weed use disorder.

  • Drugs that showed promise in preliminary research or limited clinical trials are the sleep aid Ambien, the anti-anxiety/anti-stress drug buspirone (BuSpar), and the anti-epileptic drug gabapentin, which may enhance sleep and, possibly, executive function.
  • Other agents under investigation include the dietary supplement N-acetylcysteine and drugs known as FAAH inhibitors, which may lessen withdrawal by preventing the breakdown of the bodys cannabinoids.

Bottom Line From Practical Anxiety Solutions

A person beginning to use Ambien should cut back on weed gradually to avoid withdrawal symptoms. It is best to wait until all traces of Ambien have left your system before consuming any amount of marijuana, even in modest doses, to prevent any residual toxicity. Consult a doctor if you experience any side effects from combining Ambien and weed.