IRFANA PARVEEN
By Irfana Parveen

B.Sc (Psychiatry Ward)

20 July 2022
Medically reviewed by
Sumayya Salam
Pharm D
ativan-for-seizers
Table of Contents

Ativan is the trademark name for the drug Lorazepam. Many doctors recommend it to ordinary people. Lorazepam is a medication authorized by the Food and Drug Administration to treat all types of seizures, including myoclonic, absence, partial seizures, atonic (drop attacks), and Lennox-Gastaut syndrome.

A seizure is a premature, disorderly electrical disorder in the brain. It can cause shifts in your behavior, activities or emotions, and grades of consciousness. Having 2 or more seizures at a minimum of 24 hours, an identifiable cause is generally believed to be epilepsy.

Seizures come in a variety of forms, with varying symptoms and intensity. Seizures differ regarding where they begin in the brain and how far they extend. The majority of episodes last between 30 seconds and two minutes. A seizure lasting more than five minutes is considered a medical emergency.

Seizures are more prevalent than you may believe. Attacks can occur with a stroke, a closed head injury, an infection like meningitis, or another condition. However, the etiology of a seizure is frequently unclear.

What is Ativan?

Lorazepam is a fast working drug for Anxiety. It belongs to a class of medications comprehended as benzodiazepines which operate on the brain and CNS (central nervous system) to have a soothing effect. This drug enhances the results of a particular natural chemical in the body (GABA).

The chemical formula for Lorazepam and the brand name Ativan is C15H10Cl2N2O2. Following is the chemical information about the medicine. 

Structure- 

  1. olecular Formula - C15H10Cl2N2O2
  2. Also called as - 846-49-1/o-Chlorodiazepam / o-Chloro Oxazepam
  3. Molecular Weight- 321.2

Why Is Ativan Used For Seizures?

Lorazepam acts fast in the brain to control seizure outbreaks. It usually takes 15 to 30 minutes to start working. It is taken by putting it under the tongue or between the cheek and the gum. It is observed that this way, any medicine shows high effectiveness. Diazepam gets into the brain quicker, but Lorazepam tends to last longer and help seizures over a more extended period.

How Does Ativan Work On Seizures?

Lorazepam secures benzodiazepine receptors on the postsynaptic GABA-A ligand-gated medium neuron at several locations within the (CNS), i.e., the central nervous system. It improves the inhibitory consequences of GABA, which enhances the conductance of chloride ions in the cell.

This change in chloride ions results in hyperpolarization and stabilization of the cellular plasma membrane. Its inhibitory activity in the amygdala is useful in Anxiety disorders, while its inhibitory activity in the cerebral cortex is beneficial in seizure disorders.

Ativan Dosages For Seizures 

Adults Geriatric Adults Children and Adolescents 12 years and older Children 11 years or younger
Regular dosage - 2 to 3 mg/day      Regular dosage - 1 to 2 mg/day PO Regular dosage - 2 to 3 mg/day PO Dosage is not available for Anxiety disorders
Usual dosage - 2 to 6 mg/day  Usual dosage - 2 to 6 mg/day  Usual dosage - 2 to 6 mg/day If needed- 0.025 to 0.05 mg/kg/dose PO
Max dosage- 10 mg/day PO Max dosage- 10 mg/day PO Max dosage- 1 to 10 mg/day PO -

Warnings While On Ativan

Following are the warnings for the use of the medicine Ativan. There might be severe consequences. Lorazepam mixed with alcohol has serious consequences. So always be extra sure about the precautions and warnings while taking medication.

Ativan Side Effect

Common Side effect Server Side Effect
drowsiness shuffling trek
dizziness continuous, fine tremor or inability to sit still
tiredness fever
weakness severe skin rash
dry mouth yellowing of skin or eyes
diarrhea irregular heartbeat
nausea -

Never ignore such side effects on medicines because they can cause severe issues in your mental health. And that's why you should rush to the hospital as soon as you sense any of these symptoms. 

Key points to remember

  1.  Ativan is commonly used for treating anxiety. It is a prescription medicine, meaning you cannot buy Ativan over the counter in the United States, and you always need a prescription from a licensed doctor to buy Ativan online from a certified online pharmacy or local drug store.
  2. A seizure is a premature, disorderly electrical disorder in the brain. There are many types of seizures, which range in symptoms and severity. 
  3. Lorazepam belongs to a class of drugs comprehended as benzodiazepines that operate on the brain and CNS (central nervous system) to have a soothing effect. The brand name for the same drug is ATIVAN. That means Lorazepam is sold under the name Ativan. 
  4. The dosage of Ativan for seizures varies from 1 mg to 10 mg max, depending on person to person. 
  5. There are some side effects to the medicine henceforth, and everyone should be cautious about the side effects of the drug.

Bottom Line From Practical Anxiety Solutions

Ativan‘s primary indication is to treat anxiety. However, it is approved by the FDA as a rescue medicine for prolonged seizures. Rescue seizure medicines are often used in medical care to treat a prolonged seizure that would not stop on its own.

The medicine can cause several side effects, which might be more prolonged in children. It also has an associated risk of abuse, addiction, and misuse, leading to overdose or death. Talk to your healthcare provider about the signs and symptoms of Lorazepam addiction.

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