Obsessive-compulsive disorder (OCD) is treated with clomipramine. Clomipramine belongs to the tricyclic antidepressant class of drugs. It works by raising serotonin levels in the brain, which are necessary for maintaining mental balance. Depression, panic attacks, and chronic pain have also been treated with clomipramine. Anafranil is a brand name for the drug clomipramine.(McTavish, D. and Benfield, P., 1990)
What Is The Best Way To Consume Clomipramine?
Read all of the drug guides or instruction papers that came with your prescription and follow all of the instructions on the label. Your doctor may need to modify your dosage from time to time. Follow the directions on the prescription to the letter.
Clomipramine is available as a pill to be swallowed. As the body adjusts to the medicine, clomipramine is typically taken three times a day with meals during the start of treatment. Clomipramine is commonly given once a day at bedtime after several weeks of treatment.
Your symptoms may take up to four weeks to improve. Continue to take the medication as instructed and contact your doctor if your symptoms do not improve after four weeks. Please do not take any more or less medication than is prescribed or take it more frequently than is recommended amount. Your condition will not improve any quicker, and you may experience more adverse effects, such as seizures.(Yang, Y. and Xu, L., 2013)
You may have some withdrawal symptoms if you suddenly stop using clomipramine. Some of them include:
- sleep disturbances
Strength And Recommended Dosage
Capsul Strength : 25mg, 50mg, 75mg
Dosage for OCD in adults :
- In the begining, take 25 mg orally once a day.
- Over the course of two weeks, gradually increase to 100 mg/day (divided with meals), THEN
- Once tolerated, increase to a maximum of 250 mg/day; give a single daily dose at bedtime.
Dosage for OCD in children (10 to 17years) :
- Once a day, after bedtime, take 25 mg orally.
- Maintenance dose: 3 mg/kg or 100 mg orally every day, whichever is lower.
- Maximum dose: 3 mg/kg per day or 200 mg per day, whichever is less.(Frank, P., 1977)
Side Effects Of Clomipramine
Common side effects include:
- Damage to the liver
- Loss of coordination
- Problems with sleep (insomnia)
- Problems with memory
- Concentration issues
- Vision alterations or blurriness
- Retention of urine
- Having an orgasm is difficult.
- Changes in sex motivation
- stomach ache
- Appetite fluctuations
- Failure to ejaculate
- gaining weight
- Loss of weight
- Tingling or numbness
Serious Side Effects
Contact your medical professional immediately if you experience any of this
- Breast milk production that isn’t necessary
- Periods that are irregular or uncomfortable
- Breasts that are enlarging or causing pain
- Urination problems
- Muscle tenseness
- Uncertainty (tremors)
- Changes in mental/emotional state
What Additional Medications Will Affect Clomipramine?
Consult your doctor before using an opioid, sleeping pill, muscle relaxant, or anxiety or seizure drug. A variety of medicines can harm clomipramine. Prescription and over-the-counter medications, vitamins, and herbal supplements are all included in this category. Inform your doctor about all of your existing drugs, as well as any new or discontinued medications.(Baer, L. and Greist, J.H., 1990)