Clonazepam (Klonopin)

Clonazepam (Generic Klonopin) | Drug Information, Side Effects & Dosage

When it comes to treating anxieties, some healthcare professionals suggest Clonazepam as an effective option with relatively good tolerability. This drug falls under the benzos category suitable for various forms of panic attacks and generalized disorders like a social phobia. However, what makes these pills unique from others in their category? Is there anything else apart from offering quick reliefs against even chronic conditions.

What Is Clonazepam And How Does It Work?

Keep Calm

Clonazepam is an anticonvulsant that can suppress seizures by relaxing the muscles. It also helps with panic attacks preceding your epileptic episodes. This drug is also used to treat symptoms related to chronic anxiety, panic attacks, and insomnia.

By binding to GABA receptor components, it increases the effects of GABA. It occurs because an increased affinity for GABA at their respective sites enhances ligand binding. This enhanced ligand binding of the inhibitory neurotransmitter binds to the receptors, allowing for greater conduction of chloride ions. This caused neurons to become hyperpolarized and prevented further excitation from occurring in other cells.

By increasing the inhibition of GABA, it is believed that Clonazepam can reduce excessive electrical nerve activity in CNS, which might be contributing to seizures. Concurrently, it is proposed that Clonazepam enhances GABA effects in the amygdala to inhibit neuronal activity involved in fear circuits. This mechanism assists with managing anxiety or panic attacks.

Dosage Consideration

For panic disorder treatment:

The recommended dose is 0.25 mg/day to be taken orally every 12 hours initially, though for some patients the dosages may increase up to 4 mg/day.

For seizure disorder treatment:

Seizure in adults:

The starting dose is 1.5 mg orally for every 8 hours, which can be increased by 0.5-1 milligrams each 3 days to a maximum of 20 milligrams per day if the desired effect isn’t achieved yet.

Maintenance of seizures in adults:

2-8 mg orally daily. Do not exceed 20mg per day.

Children younger than 10 years or less than 30 kg:

Dose 0.01-0.03 mg/kg/day orally divided every 8 hours, and their dosage can increase by 0.25-0.5 mg per day up to a maximum dose of 0.1-0.2 mg/kg (every 8 hours).

Maintenance dose:

0.1-0.2 mg per kg per day orally divided every 8 hours, not recommended to exceed the dose up to 0.2mg per kg per day.

Children younger than 10 years or more than 30 kg:

Take 1.5 milligrams each day, divided into smaller doses and separated by intervals of 8 hours; slowly increase the dosage until you reach your desired effects without exceeding 20 mg per day.

Maintenance dose:

2-8 mg orally; not recommended to exceed 20 mg/day.

Withdrawal Considerations

Withdraw treatment gradually over time by decreasing the dose every 3 days until completely withdrawn. Decrease it orally to 0.125 mg every 12 hours.

Clonazepam Half-Life

Clonazepam takes thirty to forty hours for half of the composition to leave the system. To eliminate all clonazepam might take several days because it is relatively slow compared to other benzodiazepines and has a low level of plasma concentration at any given time due to its slow metabolism process.

Side Effects Of Clonazepam

According to Dokkedal-Silva, Vinícius, et al. Harvard review of psychiatry 27.5 (2019) Clonazepam has a set of symptoms that you might experience if the medications are not properly regulated. As time progresses, these effects can worsen and cause more problems for your body so it is important to contact with doctor as soon as possible without delay.

Clonazepam has a set of symptoms that you might experience if the medications are not properly regulated. As time progresses, these effects can worsen and cause more problems for your body so it is important to contact with doctor as soon as possible without delay.

Some Of The Common Side Effects Are Listed Below:

  • Drowsiness
  • Sedation
  • Abnormal coordination
  • Loss of control of bodily movements
  • Depression Or symptoms of depression
  • Dizziness
  • Fatigue
  • Memory impairment
  • Respiratory disorder or symptoms
  • Confusion
  • Difficulty speaking

Some Of The Adverse Side Effects Of Clonazepam Are Listed Below:

  • Runny nose
  • Coughing
  • Urinary frequency
  • Impotence
  • Decreased libido
  • Increased salivation
  • Worsening tonic-chronic seizures

If you are suffering from any of the side effects, please see a doctor immediately. It is not healthy to expect these symptoms will disappear on their own. There’s an interaction between chemicals that can only be stopped with professional help.

Warnings And Precautions Of Clonazepam

Warnings:

Do not take Klonopin or any other anxiety medications such as Valium and Ativan if you are allergic to any of the ingredients contained in this drug or suffer from glaucoma or myasthenia gravis. Keep it out of reach of the children and away from all sources of fire as it is flammable when exposed to heat.

If an overdose occurs, seek medical help immediately, contact Poison Control Centre for further information on how to proceed with treatment.

Precautions:

Not recommended in people who suffer from neuroses, psychotic episodes, and respiratory depression, which is severe enough to be life-threatening if not treated immediately.

The drug should be used with caution in people who have abused or been addicted to alcohol because of the risk for dependence. Prolonged use may result in psychological and physical dependency.

When you are stopping clonazepam, it’s essential to do so gradually. Suddenly discontinuing the drug may cause status epilepticus-a life-threatening medical emergency requiring hospitalization for symptom control and supportive care until all seizures have ceased.

Before giving drugs to patients who have difficulty handling secretions, consider the possibility that they may produce an increase in salivation.

Clonazepam & Pregnancy

According to the study of Lin, Angela E., et al. “Clonazepam use in pregnancy and the risk of malformation”, Clonazepam is not usually safe for pregnant women. The baby might have withdrawal symptoms, which are side effects of the medication, including tremors and seizures.

Clonazepam is not usually safe for pregnant women. The baby might have withdrawal symptoms, which are side effects of the medication, including tremors and seizures.

Consult your healthcare physician & do not stop taking the drug suddenly. Your doctor can explain the risks and benefits of taking clonazepam, which may include withdrawal symptoms in you or your baby. They will also help choose a treatment that’s best for you both.

Clonazepam & Breastfeeding

If you are breastfeeding or want to breastfeed, be aware of the effect of the pill on the baby’s behavior. The following side effects may occur: not feeding, as usual, seems unusually sleepy, and unusual breathing patterns. In such a situation it is always recommended to consult a healthcare professional.

Can you buy Clonazepam without a prescription?

Clonazepam, available under the brand name Klonopin, is a Schedule IV medication. Clonazepam’s medical benefits are recognized, as well as its relatively low potential for abuse. However, its dangers and risk for abuse require federal oversight and regulation and can only be acquired using a doctor’s prescription either online or locally to treat several conditions.

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