By Irfana Parveen

B.Sc (Psychiatry Ward)

05 December 2021
Medically reviewed by
Sumayya Salam
Pharm D
Sertraline For Premature Ejaculation
Table of Contents

Research has proven Sertraline to be both safe and effective for the use of premature ejaculation. It can be more effective it is consumed alongside behavioral and psychological treatments. 

St. Luke Hospital Complex, Sydney, Australia, conducted a study to assess the efficiency of Sertraline for Premature Ejaculation.

In dose-ranging research, 46 average potent men aged 22 to 63 years (mean 42 years) with premature ejaculation were treated with oral Sertraline. All males were married or in a committed relationship. 1 minute was the average ejaculatory interval (range 0-5 min). All men were started on 25 mg of Sertraline per day, which was increased to 50 mg after three weeks and 100 mg after another three weeks. There was no formal psychosexual counseling for the men.

The mean ejaculatory interval rose to 7.6 minutes with a dose of 25 mg (range 0-20 min). The mean ejaculatory interval rose to 13.1 minutes at a dose of 50 mg (range 7 minutes-anejaculation), with four men having anejaculation. The mean ejaculatory interval rose to 16.4 minutes at a dose of 100 mg (range 7 minutes-anejaculation), with 10 males reporting anejaculation. Buy Sertraline online from a certified online pharmacy.

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One male had transitory dizziness after using 25 mg. One guy reported drowsiness and anorexia after taking 50 mg, while another had slight dyspepsia. Two men had erectile dysfunction and reduced libido after taking 100 mg, two men reported transitory drowsiness and anorexia, two men reported slight dyspepsia, and two men reported anxiety. Sertraline appears to be a promising drug for the treatment of premature ejaculation.(Arafa, M. and Shamloul, R., 2006.)

Side Effects:

Sertraline has the potential to have negative side effects. If any of these symptoms are:

  • Severe, Contact your Doctor:
  • Heartburn.
  • Weight gain.
  • Weight loss.
  • Headaches.
  • Seizures.
  • Loss of Appetite
  • Change in sex drive.

How To Consume Sertraline For Premature Ejaculation?

A person needs a prescription from their doctor to use it.

The dose can vary from patient to patient. This depends on your doctor. The dosage could go as low as 25mg to 50mg and at times to 200mg.(Sahan, A., Cubuk, A., Ozkaptan, O., Toprak, T., Ozcan, T., Ertas, K., Canguven, O. and Tarhan, F., 2020)

Other Drugs For Premature Ejaculation:

Escitalopram: Escitalopram is an antidepressant and anxiety medication. It works by assisting in the restoration of a natural substance (serotonin) equilibrium in the brain. Escitalopram belongs to the selective serotonin reuptake inhibitors class of medicines (SSRI). It may increase your energy and emotions of well-being while also reducing anxiousness resulting in a delayed orgasm.

Paxil: When administered on a chronic, 'on-demand basis following chronic treatment, paroxetine hydrochloride appears to be a helpful drug in the treatment of premature ejaculation.

Fluoxetine: The active element of Prozac, fluoxetine, has been shown to be effective in treating PE in studies. Prozac's efficacy as a treatment for premature ejaculation is thought to be linked to the relationship between serotonin levels and ejaculation.(Symonds, T., Roblin, D., Hart, K. and Althof, S., 2003)

Other Ways To Treat Premature Ejaculation:

Apart from medications, here are a few ways to treat premature ejaculation:

  • Topical products like wipes and creams.
  • Numbing condoms.
  • ZInc supplements.
  • Dietary changes.
  • Pause squeeze technique.
  • Pelvic strengthening exercises.
  • Start-stop method.
  • Professional help.

40% of Males have experienced premature ejaculation, and there’s nothing to be embarrassed about, talk it out with your partner, get to the root of the problem. Learn about your body; there’s no shame in seeking help; it's completely normal.

Don’t ignore this as a minor concern. Act on it and improve your sexual wellness.(Waldinger, M.D., 2007)

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