B.Sc (Psychiatry Ward)
19 August 2019 - 5 min read
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Buy Zoloft (Sertraline) to treat your Anxiety and Depression
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Drug Name: Zoloft (sertraline)
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Sertraline To Keep Control Of Anxiety

Battling with anxiety unceasingly can be exhausting. Leading a healthy lifestyle, with psychotherapy, can help sufferers overcome their anxiety. However, the road to overcoming anxiety may be a long and tedious one. Therefore, to help kick off the process, medications like Sertraline – an antidepressant are commonly prescribed by doctors for treating both depression and anxiety disorders.



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Sertraline For Anxiety

Sertraline is a type of antidepressant known as a selective serotonin reuptake inhibitor (SSRI). This popular drug has been used since the 1990s and works by increasing serotonin levels in your brain.

Serotonin can affect mood, sleep patterns, anxiety level, and appetite. It helps many people recover from depression with fewer side effects than older antidepressants such as tricyclics or monoamine oxidase inhibitors.

Sertraline is widely prescribed because it not only reduces symptoms associated with major depressive disorder but also decreases unwanted physical side effects compared to other medications for this condition.

Additionally, this medication may help those suffering from obsessive-compulsive disorder (OCD), panic disorder, social anxiety disorder (SAD), and post-traumatic stress disorder (PTSD).

Adverse Effects Caused By Sertraline

The medications performing on the brain have specific effects that may create uneasiness in the patients. Sertraline, when taken orally, may make a person feel tired, confused and may also create sleep disturbance.

Some standard list of adverse effects includes:

Nausea, excess perspiration, dizziness, insomnia, gastrointestinal effect, loss of appetite, heartburn, fatigue, weakness, low libido.

Impact Of Sertraline In Children

The FDA approves Sertraline only for children above 18 years with obsessive-compulsive disorder (OCD). It is not FDA-approved for treating depression in anyone below 18. The side effects observed in adults differ from that of children, such as:

Muscle twitching, nasal bleeding, urine infection, high aggression, dense menstrual periods, change in weight, slow progressive development, an obstacle in height growth.

Unless these sensations are mild, you may treat them using home remedies. However, once you observe the rise in these effects, please notify your child expert immediately.

Few Severe Side Effects Include

Sertraline is likely to cause additional effects that are rare and severe in intensity. If you experience any of the below-mentioned effects, seek medical help immediately.

Shivers, violence, aggression, feelings of hostility, suicidal thoughts, severe depression, panic attacks, irritation, difficulty in falling/staying asleep, restlessness, hallucinations, delusions, seizures, fast heart rate, less alertness, coma, irregular blood pressure, muscles pain/stiffness, respiratory depression, swelling of face, tongue, or lips, skin rashes and hives, fever, racing notions, mania, unwanted high energy, low level of sodium, loss of memory, slurred speech, blurred vision.

If you’re experiencing anything from the above list or something not mentioned here but affecting your physical and mental well-being, please reach out to the concerned expert.

Dosage For Sertraline

Your healthcare provider decides the amount of Sertraline and the duration, of course, depending on:

  1. Your age
  2. The health condition you’re suffering through
  3. The intensity of the illness
  4. Past medical history and gender

Strengths and Forms of Sertraline

Generic Sertraline is available in oral form. You may get the tablets in strength ranging from Sertraline 25 mg, 50 mg, and 100 mg, respectively. It is available in a liquid solution as well, with a strength of 20mg.

While Zoloft is the brand name available in film-coated tablet form that can be taken directly by mouth, Zoloft 25 mg, 50mg, and 100 mg are the available strengths. Dosage Forms and Strengths

  • 25 mg tablets: light green, engraved on one side with ‘ZOLOFT’ and the other side with ’25 mg.’
  • 50 mg tablets: light blue, engraved on one side with ‘ZOLOFT’ and the other side with ’50 mg.’
  • 100 mg tablets: light yellow, engraved on one side with ‘ZOLOFT’ and the other side with ‘100 mg.’

The oral solution of Zoloft is a clear solution containing sertraline hydrochloride (HCL) equivalent to 20 mg of Sertraline per mL along with 12% alcohol retaining a menthol scent. It is supplied in a 60 mL bottle with an accompanying calibrated dropper having 25 mg and 50 mg increment marks.

Doctors initiate with the lowest dose possible so that it does not interact poorly with the system and shows effective results at the same time. So, before you’re planning to hook yourself to Sertraline, take your doctor’s advice and mutually plan a strategic dose for your well-being.

This has been explained well by Murdoch, David, and Donna McTavish. In 1992 “Sertraline.” Drugs.


Interactions occur when you combine Sertraline with other medications. The dual effect of the combination therapy may create havoc within your system, causing you to pay a severe health penalty.

For instance, drugs like SSRI, Ibuprofen, and aspirin that belong to Non-steroidal anti-inflammatory drugs may rush the chances of bleeding, inflammation, and bruising. Combining lithium with Sertraline again improves the risk of serotonin syndrome.

Combining opioids like Tramadol with Zoloft, an SSRI member may include drowsiness and other severe mental effects.

Antidepressants like desipramine may result in piling up of molecule concentration in your body. Ask your doctor to adjust the sertraline dosage if you’re already on a tricyclic depressive course.

When they come in contact with Sertraline, some other medicines may emit negative signs from your body. The list includes:

When used through IV mode, Linezolid may lead you to a bad mood, irritation, or high mental pressure as it may increase the hormone level.

You may also go through cardiovascular depression if you happen to take pimozide with Sertraline.

Monoamine oxidase inhibitors are one of the major drug classes with an anti-depressive ability. If you take a brand of MAOIs with SSRIs medications, the ideal gap should be 14 days until the effect is diminished. As having them together will make hormonal imbalance creating psychological disturbance within an individual.

Lastly, The U.S. Food and Drug Administration recommends not drinking alcohol while you take Zoloft because it can increase the nervous system side effects of Zoloft, including dizziness, drowsiness, and difficulty concentrating in some individuals.

Also, not every individual may experience drug interactions with these medications. The information displayed is the possible general interaction observed among the majority of the people.

To know the specific result in your case, please discuss it with your healthcare service professional. Also, share other health supplements like vitamins, protein, herbal products, and over-the-counter medicines you’re taking to be well aware of the possible interactions from them).


A few clinical pieces of research have stated that about sixty percent of the patients who abruptly quit taking anti-depressive pills are likely to suffer from withdrawal signs. However, the intensity of the symptoms is different for everyone.

The typical withdrawal symptoms include:

  • Fever
  • Cold
  • Nausea
  • Change in sleep schedule
  • Hormonal imbalance
  • Mental disturbance
  • Anxiety

Other than common signs, there is a potential drawback leading to severe life-threatening events. The rare symptoms include:

  • Light-headedness making it challenging to walk from the drawing-room to the bedroom.
  • Gastrointestinal problems like diarrhoea resulting weakness
  • Attacking your temper leading to anxiety, stress, panic attacks, depression, life-taking thoughts, and mania.
  • Unusual nightmares or insomnia.
  • An increase in electrical activity leading to shivering and shock in your brain and loud ringing in your ear is a bizarre symptom.
  • Muscle spasms, slurred speech, tremors, or seizures.

As spoken about in 2015 by Fava, Giovanni A. “Withdrawal symptoms after selective serotonin reuptake inhibitor discontinuation: a systematic review.” Psychotherapy and psychosomatics.


The FDA has readily listed the warning for users’ better health prospects. The potential effects are displayed to protect patients from abusing or misleading the medication for unethical purposes.

Some users have suicidal thoughts when first consuming an antidepressant. Stay alert to drastic changes in your symptoms or mood. Report any new or worsening symptoms to your healthcare provider.

Seek medical help immediately if you have symptoms of serotonin syndrome, such as agitation, hallucinations, fever, sweating, shivers, rapid heart rate, muscle stiffness, loss of coordination, nausea, vomiting, diarrhoea, or twitching.

The disadvantages of taking SSRIs during pregnancy may lead to premature delivery, underdevelopment of the foetus, and withdrawal symptoms for the child after birth. Use of Sertraline while breastfeeding is not recommended either.

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