The Controlled Substances Act of the U.S. regulates the use of drugs by placing them into 1 of 5 descending schedules ranging from Schedule I to Schedule V. Tapentadol is a centrally acting, atypical analgesic with a novel mechanism of action that is a combination of ?-opioid agonist activity and norepinephrine reuptake inhibition.
The United States FDA approved Tapentadol's immediate release in December 2008 and the extended-release formulation (Nucynta ER) in August 2011. The prevalence of Tapentadol abuse and diversion (E.R. and I.R.) has been low compared with other prescription opioid compounds, mainly when considered at the population level. Continue reading for more details.
Tapentadol (Nucynta) is a central-acting opioid medicament of the benzenoid class for alleviating severe acute pain for a short period when other medications become intolerant. It reduces pain perception by altering the receptors of the brain.
It increases extracellular norepinephrine (N.E.) due to its dual mechanism of action, i.e., it acts on mu-opioid receptor (MOR) agonist and noradrenaline reuptake inhibition. It shows its effect within 30 minutes of administration, lasting nearly 4-6 hours.
Nucynta drug is habit-forming even at regular doses. It should be taken exactly as prescribed by the doctor. Also, it should be swallowed whole with a glass of water to avoid exposure to a potentially fatal dose.
Tapentadol should not be taken if you are allergic to it or if you have-
Tapentadol (Nucynta) is an FDA-approved medicine for managing short-term (acute) pain that is severe enough to take opioid analgesics and when other pain medications become intolerant.
Tapentadol is highly useful in the following conditions-
In patients with chronic pain from Fibromyalgia, the increase in inhibition of endogenous pain by Tapentadol was translated into analgesia in patients with a normal CNFS. This medicine is unsafe for pregnant or breastfeeding women and should inform the healthcare practitioner.
Tapentadol (Nucynta) is an opioid analgesic that may be addictive, even at its regular dose. It should be taken as prescribed by the doctor, and instructions on the prescription label should be read carefully with all medical guides. Also, the following things should be kept in mind while taking this medicine:
Tapentadol (Nucynta) is an effective drug in treating moderate to severe pain and is most effective when other drugs become intolerant. But its efficacy depends on various factors, i.e., dosage and administration time, medical history, body weight, age, tolerance, interaction with other drugs, storage of drugs, etc.
Storage of drugs is a crucial aspect of the drug control system to ensure that the quality of drugs is not compromised.
Tapentadol (Nucynta) should be stored at room temperature, away from moisture and heat. Also, it should be stored safely so that no one else administers it accidentally or purposely.
These pills should be kept out of reach and sight of children and pets. Also, the track of medicine should be adequately maintained to know how much medication is left or missing.
Nucynta drug is usually tolerated well, but minor adverse effects can be observed, such as vomiting, headache, itching, dry mouth, drowsiness, and dizziness. A life-threatening allergic reaction to the drug is possible in a few cases.
Thus, various precautions should be taken with this drug. This drug should not be self-administered or stopped without a doctor's consultation.
If this drug is stopped suddenly, a person might experience withdrawal symptoms, especially if the drug has been taken longer. These symptoms include tremors, sweating, diarrhea, Anxiety, insomnia, and hallucinations.
Tapentadol is an opioid analgesic medication that may be habit-forming even during regular use. Thus, it should be taken as prescribed by your healthcare practitioner. It treats moderate-to-severe acute pain, neuropathic pain, osteoarthritis pain, chronic pain, and Fibromyalgia.
It is mainly when other painkillers become intolerant. Also, precautions should be taken before taking this medication and ensure adequate drug storage. In case of severe side effects are observed, seek immediate help from the healthcare practitioner.
