By Irfana
B.Sc (Psychiatry Ward)
28 April 2022 -
Medically reviewed by
Dhanashree
MA (Psychology)
Ativan and Alcohol
Table of Contents

What Is Ativan?

Anxiety is treated using this drug. It has a very calming effect on the brain and nerve; This medication improves the effects of a natural substance in the body. (Ghiasi, N., Bhansali, R.K. and Marwaha, R., 2021)

Generic name: Lorazepam

Ativan is an antidepressant that is not available over the counter. You can  buy Ativan online from a certified online pharmacy, but first, you should consult your health care provider before consuming this medication.

Forms:

Ativan is available in two forms: pills and liquid.

Intravenous (IV) injection of Ativan solution. 

Strengths:

How Should You Take Ativan?

As instructed by your doctor, take this medication by mouth with or without food. The dosage is determined by your medical condition, age, and treatment response. To receive the best benefit from this drug, take it on a regular basis as advised by your doctor. Use it at the same time every day to help you remember.

Dosage:

Orally, Ativan (lorazepam) is delivered. Dose, frequency of administration, and length of therapy should all be tailored to the patient's response for best outcomes. Tablets in the dosages of 0.5 mg, 1 mg, and 2 mg are available to help with this.

The typical daily dosage range is 2 to 6 mg in divided doses, with the highest amount taken before night. However, the daily dosage can range from 1 to 10 mg.

Most people with anxiety require an initial dose of 2 to 3 mg/day, administered two or three times per day.

A single daily dose of 2 to 4 mg, generally around bedtime, may be used for insomnia caused by anxiety or transitory situational stress.

A starting dosage of 1 to 2 mg/day in divided doses is indicated for elderly or disabled patients, to be modified as needed and tolerated.

When taking Ativan (lorazepam), the dosage should be gradually increased.  (Ghiasi, N., Bhansali, R.K. and Marwaha, R., 2021)

Ativan Side Effects:

  • Extreme sleepiness,
  • Confusion,
  • aggression,
  • Hallucinations,
  • a worsening of sleep issues,
  • a quick sensation of restlessness or enthusiasm,

These are some of the common symptoms

The following are the most common Ativan adverse effects:

Ativan And Alcohol:

Ativan is a Schedule IV controlled substance that can lead to addiction and misuse. While benzodiazepines like Ativan can be abused on their own, they are frequently combined with other drugs like opioids and alcohol.  (Ghiasi, N., Bhansali, R.K. and Marwaha, R., 2021)

Studies:

According to studies, 3 percent to 41% of alcoholics use benzodiazepines to enhance the effects of alcohol or reduce the effects of withdrawal.

Because Ativan and alcohol have comparable effects on the brain and body, consuming both at the same time can intensify those effects, sometimes fatally. They lower your heart rate and respiration. The combined effects of the two can be stronger than if they were ingested separately. Severe sleepiness, breathing issues, coma, and death can result from the combination.

Mechanism:

When you drink alcohol, it passes through your digestive tract and into your bloodstream, where it travels throughout your body, including to your brain.  (Ghiasi, N., Bhansali, R.K. and Marwaha, R., 2021)

How It Affects The Brain?

When alcohol enters the brain, it affects several neurotransmitters, including inhibitory (GABA) and excitatory neurotransmitters. It binds to receptors and increases GABA activity while decreasing glutamate's action on receptors. In summary, it boosts inhibitory neurotransmitter activity while lowering excitatory neurotransmitter activity.

Increased dopamine activity in the brain is also linked to alcohol consumption. This surge in dopamine is followed by feelings of pleasure and reward, which can encourage people to drink more.

Who Should Take Ativan:

Ativan is used to treat anxiety disorders or to relieve the symptoms of anxiety or anxiety associated with depressive symptoms in the short term. Anxiety or tension caused by everyday stress normally does not necessitate the use of anti-anxiety medication.

Who Should Not Take Ativan?

This medication should not be used if you have any of the following conditions. It is advised to consult your doctor immediately if you face any of these symptoms:

  • Suicidal thoughts due to a low level of albumin proteins in the blood
  • drug abuse and drunkenness with alcohol
  • liver issues asthma
  • liver illness that is serious
  • Apnea (sleep deprivation)
  • Due to liver illness, pregnancy harmed brain function.

 In case Of Pregnancy:

  • Ativan and generic lorazepam are classified as pregnancy category D drugs, meaning they pose a risk to pregnant women and their unborn children and should be avoided throughout pregnancy.  (Ghiasi, N., Bhansali, R.K. and Marwaha, R., 2021)

Conclusion:

Do not consider consuming alcohol with this medication as it can cause a lot of physical and mental distress. This medication also causes lightheadedness, and consuming alcohol with it can worsen its effects which can cause extreme dizziness.

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