By Irfana
B.Sc (Psychiatry Ward)
19 September 2021 -
Medically reviewed by
D. Pharm
Understanding Xanax And Onax For Anxiety And Depression
Table of Contents

Anxiety is a sensitive matter that lot of individuals suffering with, and so to manage it, the treatment needs to be just right. Choosing the wrong treatment or medication can result in worsening the condition. Xanax and Onax are two anxiolytics that people often get confused with.

Hence, we have given a brief idea further that shows how Xanax and Onax differ with each other, so keep reading!

Learn The Difference Between Onax And Xanax?

Onax is a tablet used for the management of an anxiety disorder and the short-term relief of anxiety. This drug works by binding at several nerves within the brain and affecting the chemical action of the body to generate a depressive effect on the brain activity.

This medicine is available in the form of a tablet, while Xanax is available in an extended-release tablet and immediate-release as well as oral medicine.

Xanax is a benzodiazepine, which can calm and relax the central nervous system. This drug works by increasing activity at receptors for gamma-amino butyric acid (GABA) neurotransmitters that are responsible for sleepiness.

Xanax is not available over the counter so you always need prescription to buy xanax from any pharmacy.

Xanax has many side effects though, including dizziness or drowsiness that may cause you to fall asleep while driving or doing another physical activity in which you need concentration.

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Conditions Treated By Xanax And Onax

Xanax is helpful for any individual suffering from condition like anxiety disorders and anxiety caused by depression. Similar conditions include:

  • Anxiety
  • Panic disorder
  • Repeated episodes of anxiety
  • Anxiousness associated with depression

The conditions related to mental health is generally treated by Xanax. It ultimately acts on the nerves and brain to generate a calming effect that enhances the impact of a different natural chemical in the body’s system.

Onax works on the conditions like nausea and vomiting due to certain medical conditions like stomach upset. It can also be helpful in preventing nausea and vomiting caused by surgery, cancer drug therapy or radiation treatment.

Abuse And Withdrawal Of Xanax

Users of Xanax may develop tolerance to the drug quickly, increasing their consumption in order to feel any effects. When someone with a Xanax addiction stops taking the drugs they will likely experience withdrawal symptoms like anxiety and restlessness that can potentially be dangerous or even life-threatening if left untreated.

If you start to feel withdrawal-like symptoms, this may mean that your body has become physically dependent on the substance. If tolerance is present and there are signs of addiction, it’s clear what kind of drug dependence has developed.

There’s a case study on a review of Xanax abuse and withdrawal and why it is the most prescribed medicine for the treatment of generalized anxiety. The study was done by Ait-Daoud N, Hamby AS, Sharma S, and Blevins D. A Review of Alprazolam Use, Misuse, and Withdrawal.  (

Xanax withdrawal symptoms start within hours of the last dose and peak in severity after 1-4 days. Symptoms include:

  • Headaches
  • Blurred vision
  • Muscle pain
  • Tremors
  • Diarrhea
  • Numb fingers
  • Sensitivity to light and sound
  • Loss of appetite
  • Insomnia
  • Heart palpitations
  • Sweating
  • Anxiety
  • Panic
  • Paranoia
  • Seizures

Onax And Xanax Which Is More Effective?

It is shown in a study that by comparing Onax and Xanax, both these drugs are found to be equally effective for treating symptoms like anxiety. In addition, the onax has fewer withdrawal symptoms and fewer side effects as compared to Xanax.

We know Onax is more effective than Xanax as the side effects are usual like dizziness, nausea, nervousness, tiredness, headache, and trouble while sleeping may also occur. We still suggest you consult a doctor if any of these stages or side effects get worse.

The drug has its whole clinical impact on the body. So it can be good medicine to manage anxiety symptoms rapidly.

Common Side Effects Of Onax Vs. Xanax

We have seen typical side effects that usually are not much harmful to the body but can affect your metabolism.

The most common side effects of onax are weakness and dizziness. Sometimes patients taking onax may also experience excitement, nervousness, and nausea.

Let us talk about the adverse effects of Xanax, which are sedation, dizziness, and weakness. The side effects are very much similar to onax, like lightheadedness and headache.

You may not be heard of other products of memory problems, dry mouth, disorientation, euphoria, seizures, vertigo, vision changes, slurred, coma, and respiratory depression. It also has an impact on your stomach, creating constipation and diarrhea.

Drug Interactions Of Onax And Xanax.

After taking onax, one should not use monoamine oxidase inhibitors within 14 days because the combination of the drugs would cause an increase in blood pressure or serotonin syndrome.

Both the drugs are metabolized or processed by an enzyme called cytochrome (CYP 3A4). Many drugs inhibit CYP3A4, preventing onax and Xanax from being processed, leading to the buildup of these drugs. These include diltiazem, erythromycin, and others. In addition, grapefruit juice can inhibit the metabolism of Xanax or onax.

On the other hand, many medications are inducers and speed up the mechanism of these drugs. As a result, they might not be so effective, including carbamazepine, phenytoin, barbiturates, and rifampin.

These drugs cannot be taken with painkillers because of the increased risk of overdose and respiratory depression, possibly even death. If no other medicine is possible, the patient must receive both drugs at a low possible dose and for a short time. For detailed information about these drugs, consult your healthcare provider.


When taking these drugs with alcohol and opioid medicine, fatal side effects can occur.


Serotonin syndrome is a life-threatening state that could occur if there is a rise in serotonin levels. Conditions usually happen because of the combination of drugs such as antidepressants that raised the serotonin levels too much. It could become mild to severe and can lead to death.

Patients suffering from any liver or kidney problems must not use Onax.


The warning itself is mentioned in the box of the medicine required by the FDA. It must not be taken with opioid painkillers, leading to an extreme condition like severe respiratory depression, coma, or death. If the combination of opioid and benzodiazepine is not avoided, the patient should be prescribed a low dose for a short time until the adverse effects are known.

If you have a liver problem, talk to the doctor about that before taking Xanax.

The risk of suicide has been seen in patients with depression, and also it shouldn’t be given to patients with lung problems such as COPD.

The drug may cause psychological and physical dependence, leading to increased risks like taking medication for a longer time and alcohol abuse because it is seen that patients with depression and panic disorder might use higher doses of Xanax.

Xanax dosage:

Adult Dose For Anxiety:

Immediate-release tablets: 0.25 to 0.5 mg orally administered 3 times a day
Maximum dose: 4 mg/day

Adult Dose For Panic Disorder:

Immediate-release tablets: 0.5 mg orally administered 3 times a day
Maximum dose: 10 mg/day

Extended-release tablets:
Initial dose: 0.5 to 1 mg orally once a day
Maintenance dose: 3 to 6 mg orally per day, preferably in the morning
Maximum dose: 10 mg/day

Onax Dosage:

Dose for adults- 0.25-0.5 milligrams three times a day (not more than 4 milligrams in one dosage).

The maximum dose of Onax for an adult is four milligrams per day and there may be risks associated with addiction if you have a history of alcohol or drug abuse.

This medicine has not been studied in children. It is unknown if Onax is safe for kids under 18 years old, so please consult your doctor before you give it to them.


As we have discussed the comparison of these two medications and showed how to use them to treat anxiety.

Adverse effects of both these drugs are primarily similar to each other, and we have acknowledged several warnings of Onax and Xanax.

Use these drugs wisely with prescriptions and doctor consult.

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