By Irfana
B.Sc (Psychiatry Ward)
28 June 2022 -
Medically reviewed by
Freny
D. Pharm
Paxil For PTSD
Table of Contents

What is post-traumatic stress disorder (P.T.S.D.)? 

It is a psychiatric disorder that may occur to someone who has an experience or witnessed a past traumatic event similar to a terrorist act, a natural disaster, a severe accident, war/combat, or who has been through life-threatening events or sexual violence or severe injury is a post-traumatic stress disorder (PTSD).

Previous to this, it was also known by the name of 'shell shock' during world war I and as 'combat fatigue' during the phase of World War II, but it doesn’t need to occur to someone from are war veterans only. PTSD can occur to anyone and with any traumatic background. Lots of people face the PTSD problem with a background of any ethnicity, nationality, or culture at any age. Approx. 3.5 percent of U.S. adults are affected by PTSD., and an estimate of one in 11th Americans is targeted od PTSD. This number doubles in women. (Javidi, H. and Yadollahie, M., 2012)

  1. U.S. Latinos, 
  2. African Americans, 
  3. American Indians – are the three ethnic groups disproportionately affected and have higher rates of PTSD than non-Latino whites.

THE FIRST-CHOICE TREATMENT FOR P.T.S.D.

Most doctors recommend SSRIs and SNRIs as first-choice medications for people with PTSD. 

Paxil 

Paxil is the best SSRI medicine available on the market. Paxil work by raising serotonin levels in the brain. Serotonin is a chemical signal used for communication within the brain and nerves throughout the body.

People with PTSD may have changes in these chemical signals that contribute to PTSD symptoms. Twelve weeks is the pre-estimated timing for these medicine takes to work. 

Paxil is not available over the counter in US. It is only available with a prescription. Always buy Paxil online from a certified online pharmacy and be cautious of fraudulent websites.

Paxil is FDA-approved for treating PTSD and is one of the most common medications for this condition. In studies, Paxil effectively reduced PTSD symptoms in over 50% of those taking it and was well-tolerated. (Bosn J Basic Med Sci. 2008)

 Study shows over 54 % to 62% of the patients get the best possible results out of the Paxil. 

common side effects of Paxil:

  • Nausea
  • Diarrhea
  • Upset stomach
  • Weight Gain 
  • Weight Loss
  • Sex disturbances 

Efficacy of Paxil

Paroxetine is more effective than placebo, with fewer patients who did not experience improvement in symptoms of at least 50% (random effect RR 0.83, 99% CI 0.77–0.90). Significantly more patients in the paroxetine group than in the placebo group left their respective studies because of side effects (random effect RR 1.77, 95% CI 1.44–2.18) or experienced suicidal tendencies (odds ratio 2.55, 95% CI 1.17–5.54). 

  • What is the success rate of Paxil?

It is observed that 12 weeks of treatment resulted in - remission rates were 61.2% and 44.0% for placebo, 72.9% and 52.5% for paroxetine IR, and 73.7% and 56.2% for paroxetine CR, respectively. (Tyuvina, N.A., Prokhorova, S.V. and Maksimova, T.N., 2012)

  • User Guide For Paxil

first of all, it is the most thing to follow your associated doctor, to improve your use case and user experiences. following is the information based on the general idea and general consumers. Don’t do changes to your timetable unless consulting your doctor. 

Dosages for Post-Traumatic Stress Disorder: 

  •   Adults - start with 20 milligrams (20 mg) or better to start even with 10mgs as per your doctor’s recommendations. 

your doctor may feel to adjust your dosage. however, the dose should not be more than 50 mg to 25 ml per day. 

  • Older adults - For older adults start with 20 milligrams of the 10 MLS of this specific medicine, which usually should be taken in the morning. it should not exceed more than 40 mg or 20 ml per day. 
  • Children- For children, every dose should be prescribed by the accosted doctor.  

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.
  • Keep out of the reach of children.
  • Do not keep outdated medicine or medicine no longer needed.
  • Ask your healthcare professional how you should dispose of any medicine you do not use.

WARNINGS OF PAXIL

FDA Warnings-

  • Antidepressant medications may increase suicidal thoughts and behaviors. Especially within the first few months of treatments or the dose is changed. 
  • Paroxetine is not approved for use in children.

Serotonin syndrome warning - This drug can cause potentially life-threatening conditions called serotonin syndrome. Many medications can cause this type of syndrome. The symptoms of the syndromes are agitation, hallucinations, confusion, and trouble thinking. 

Worsened depression warning - In some cases, Paxil can worsen your depression if you experience unusual behavior changes, especially during the first few months of the treatment.

Stopping treatment warning - If you are stopping treatment of this drug, it needs to be done gradually. Don't stop taking drugs abruptly. You may face some withdrawal symptoms. 

Sexual problems warning - This drug can cause sexual dysfunction. Symptoms may include a decrease in sex drive, delayed orgasm, or an inability to have an orgasm. 

Increased bleeding warning - This medicine may increase your risk of bleeding and bruising, especially if taken with aspirin. 

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