By Irfana
B.Sc (Psychiatry Ward)
23 May 2022 -
Medically reviewed by
D. Pharm
Is Trazodone a controlled substance?
Table of Contents

In the world full of medical dependency for the condition you face, it should be necessary to get treated with a perfect drug. The other important aspect for looking at this scenario is finding a medicine that is not a controlled substance. So here the question arises, is trazodone a controlled substance?

Trazodone belongs to the drug class of Serotonin receptor antagonists and reuptake inhibitors. It is also available in its brand versions known as Desyrel, Desyrel Dividose, Oleptro.

Trazodone is used to treat conditions such as depression and Major disruptive disorder. It might also get mood, energy and appetite back with the medicine. Trazodone is also used in treatment such as anxiety, panic attacks and even insomnia.

This medicine was approved by the FDA on 02 February 2010. It is wholly responsible for any medicine that has to be sold legally. Buy Trazadone online from a certified online pharmacy. It is a prescribed medicine. Without the approval by the FDA, the medicine can be dangerous as well. (Haria, M., Fitton, A. & McTavish, D. Trazodone)

What is a Controlled substance in medicine?

Controlled substances are prescription drugs that have a capability of making it addictive or abusive to the person consuming the medicine. Prescription-based medicines are always used to treat specific conditions. Controlled substances are more dangerous and can be observed to have negative effects that would affect a person. Medicines are regulated by the federal government. If someone is using it without a proper prescription, they can be behind the bars or can face severe consequences from the law. 

Does Trazodone come under the controlled substance Act?

A special Act that has been imposed for controlled substance medications. In this act, the drugs were classified into different categories such as schedule 1 to 5. It has high chances of dependency and has no medical use in schedule 1 drugs. In schedules 2 to 5, medicine has fewer addiction properties and more medical usage. Especially in schedule 5, it has the lowest possibility for abuse. 

Most of the medicines that fall under narcotics are addictive. Narcotics relieve pain by acting directly on the brain. But Trazodone doesn't belong to a Narcotic. 

By now you must have got an idea about the Act that was amended and now you should know is really a trazodone a controlled substance or not?

Trazodone is not a controlled substance nor a narcotic. Before consuming Trazodone, you should be cautious with its addictiveness. There are very few chances of people getting addicted. People are mostly suggested to have the lower dose to treat insomnia, those facing depression. It has a very low possibility of abuse.

You should know why Trazodone doesn't fall in a controlled substance from the working pattern of medicine on the body.

Body mechanism of Trazodone.

Trazodone is an antidepressant medication that helps you deal with depression and other related problems. It works on the brain directly. Serotonin is a chemical that gets released into the brain after consuming Trazodone and helps you make a stabilised mood. (Azadzoi, K.M., Payton, T., Krane, R.J. and Goldstein, I., 1990)

Side Effects of Trazodone

Before consuming Trazodone, you should know about its side effects. Side effects are usually divided into two variations such as common and severe. If you find any of the common side effects do consult a doctor before it gets severe. If at all you feel severely affected, then get medical help as soon as possible.

Common side effects:

  • Blur in vision
  • Blocked nose
  • Weight loss
  • Drowsiness
  • Dizziness

Severe side effects

Precautions that you should take

Some important things that you should keep in mind before consuming Trazodone are as follows:

Do not take the medicine if you are suffering from:

  • Liver issues
  • Kidney problems
  • Seizures
  • Heart attack
  • Bipolar disorder

Some things that you should not be doing:

  • Not safe when you are breastfeeding
  • Do not take medicine if you are pregnant
  • Not good for people under 18 years.
  • You should not drink alcohol.

Drugs Interactions:

Some of the medicine that may interact with Trazodone are as follows:

  • Tramadol
  • Warfarin
  • Jantoven
  • Sumatriptan
  • Treximet


Trazodone, a medication that is used to treat depressive disorder and help you get out of the situation smoothly. Working of the medication on the body is directly through the brain. This is not an addictive medicine that may affect you. Do not take the medication for a longer period of time. There are various side effects of Trazodone that will affect you from which dizziness and drowsiness would be the most common side effects. To get a Trazodone medicine you need to get a compulsory prescription from the doctor.

What's on your mind?

Start a conversation ,Post with kindness.